In this episode, I talked with Dr. Dena Grayson, a physician–scientist with over two decades in biotech drug development. At the time of this recording, she was SVP and Head of Clinical Development at Keros Therapeutics, leading programs in rare bone marrow disorders, and she has since become SVP of Clinical Development and Medical Affairs at Kyverna Therapeutics. Earlier in her career, she helped advance Repatha at Amgen, and her path has also included running for Congress and serving as a national media voice during COVID.

Dena shares what it was like being the only MD–PhD in Amgen’s business development group, how she transitioned into clinical development, and the lessons she carried forward from her time in both politics and national media, where she became a trusted voice during the COVID pandemic. We dive into the real difference between presenting “the what” and explaining “the so what,” and why communication often makes or breaks careers in biotech.

Alongside her professional journey, Dena opens up about the wildest recruitment experience she’s ever had, her approach to building strong teams, and why patience in hiring beats rushing a decision. And in our quick-fire round, she shares stories from her days as a state champion soccer player, her love of surfing, and how she unwinds outside biotech.

(Find out more in the episode.)

Here’s What You’re In For

1. How a political campaign loss led to a media career during COVID
2. How to handle interviews when you’re introverted
3. The kinds of questions that truly impress hiring managers

Timestamps

01:10 – Landing her first industry role at Amgen

03:24 – Repatha and investigational therapies at Keros

04:49 – Surfing, soccer, and state championships

07:08 – From political spouse to running for Congress

08:42 – Becoming a media commentator during COVID

10:41 – Communication lessons: from “what” to “so what”

15:14 – Advice for introverts in interviews and early career roles

17:37 – How thoughtful questions can change the dynamic in an interview

21:02 – Nearly 20 years as a hiring manager: what’s changed and what hasn’t

23:11 – Advice for junior hiring managers and why patience matters

25:37 – A candidate with a completely fabricated CV—the wildest recruitment story

About Dena

Dr. Dena Grayson is a physician–scientist (MD, PhD) with over 20 years in biotech drug development. At the time of this recording, she was SVP and Head of Clinical Development at Keros Therapeutics, leading programs in rare bone marrow disorders, and she has since become SVP of Clinical Development and Medical Affairs at Kyverna Therapeutics. Earlier in her career, she helped advance Repatha at Amgen, and her path has also included running for Congress and serving as a national media voice during COVID, experiences that shaped her belief that communication is as critical as science in driving biotech forward.

Connect with Dena:

1. LinkedIn: https://www.linkedin.com/in/denaminninggrayson/
2. Website: https://kyvernatx.com/

About me

My name is Charles Spence and I lead Discera. After many years working in the life-science recruitment world, I decided to work for myself. Before doing...