Cracking the cholesterol code: Dr. Rob Hegele on the predictive power of genetics
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Cracking the cholesterol code: Dr. Rob Hegele on the predictive power of genetics
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When it comes to predicting your health, the answer often lies in your DNA.
That's according to Dr. Rob Hegele, whose life's work has led to numerous breakthroughs for patients combatting cardiovascular disease. In this episode of The Catalysts, we catch up with the 2026 Canadian Medical Hall of Fame inductee to learn about reading DNA, treating high cholesterol, witnessing groundbreaking research and the art of curiosity and discovery.
Dr. Rob Hegele is a Distinguished University Professor in the Departments of Medicine (Division of Endocrinology) and Biochemistry at the Schulich School of Medicine & Dentistry. He is a Scientist at the Robarts Research Institute, where he serves as Director of the London Regional Genomics Centre.
He is also the holder of the Edith Schulich Vinet Chair in Human Genetics, the Jacob J. Wolfe Distinguished Medical Research Chair in Human Gene Function and the Martha G. Blackburn Chair in Cardiovascular Research.
Related links:
- The London Regional Genomics Centre
- The Lipid Genetics Clinic
- Dr. Robert Hegele inducted into the Canadian Medical Hall of Fame
Episode Chapters
- 0:00 – Intro
- 0:37 – Predicting health with genes
- 9:19 – On treating high cholesterol
- 14:59 – The power of genetic diagnoses
- 17:23 – The birth of statins
- 21:12 – Theories on cholesterol
- 26:45 – Dr. Hegele's musical origins
- 30:12 – The art of discovery
- 35:50 – The future of cardiovascular disease