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The podcast episode featured a discussion with Dr. Martijn Figee and Dr. Alexander Charney from the Icahn School of Medicine at Mount Sinai about deep brain stimulation (DBS) as a potential treatment for schizophrenia.

The doctors explained that DBS is a neurosurgical procedure involving the implantation of electrodes to target specific brain circuits, offering a durable treatment option for severe, treatment-resistant symptoms like hallucinations and delusions.

They shared that initial results from a small number of patients have been promising, with some experiencing immediate and significant symptom reduction.

The treatment is currently in the experimental stage, with ongoing clinical trials at Mount Sinai and Johns Hopkins. The ideal patient for DBS would have chronic, medication-resistant symptoms and the ability to provide informed consent and comply with follow-up care.

The conversation also touched on the challenges of schizophrenia research, the hope for future advancements, and the importance of participation in studies and brain donation for scientific progress.

Link:

https://icahn.mssm.edu/research/blau

Mindy and her book: https://mindygreiling.com/

Randye and her book: https://randyekaye.com/

Miriam and her book: https://www.miriam-feldman.com/

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Randye Kaye
Mindy Greiling
Miriam (Mimi) Feldman