Biologics, Inflammation, and Gums: The RA–Periodontitis Link
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Biologics, Inflammation, and Gums: The RA–Periodontitis Link
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Rheumatoid arthritis and periodontal disease share more than chronic inflammation — they are biologically connected. Modern biologic therapies used to treat rheumatoid arthritis target key inflammatory pathways that also play a central role in periodontal tissue destruction.
In this episode, we explore how biologics such as TNF-α inhibitors and IL-6 blockers may influence periodontal health, potentially reducing gum inflammation, bleeding, and bone loss. We also discuss the bidirectional relationship between rheumatoid arthritis and periodontitis, and why collaboration between rheumatologists and dental professionals is essential for comprehensive patient care.
Understanding this connection helps shift the focus from treating isolated diseases to managing systemic inflammation as a whole.
Petit C, et.al. Impact of treatment of rheumatoid arthritis on periodontal disease: A review. Mol Oral Microbiol. 2024 Aug;39(4):199-224. doi: 10.1111