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Beta Finch - Pharma & Biotech - EN

Beta Finch - Pharma & Biotech - EN

著者： Beta Finch
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Leading pharmaceutical and biotechnology companies. AI-powered earnings call analysis for Pharma & Biotech (PHARMA). Two AI hosts break down quarterly results, key metrics, and market implications in digestible podcast episodes.2026 Beta Finch 個人ファイナンス 経済学
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  • AbbVie Q2 2026 Earnings Analysis

    AbbVie Q2 2026 Earnings Analysis
    2026/07/31
    More earnings analysis: https://betafinch.com
    Groups: PHARMA (https://betafinch.com/groups/PHARMA)
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    ALEX: Welcome to Beta Finch, your AI-powered earnings breakdown. Today we're digging into AbbVie's second quarter 2026 results, and this podcast is AI-generated content for educational and entertainment purposes only. Nothing we discuss should be considered investment advice. Always do your own research and consult a qualified financial advisor before making any investment decisions.

    JORDAN: And Alex, this was another really strong quarter for AbbVie. Let's just get right into the numbers.

    ALEX: Yeah, so adjusted EPS came in at $3.65, which beat guidance by six cents. Total revenue was nearly $17 billion, up 10.2% year over year, and that beat expectations by $300 million. On the back of that, they raised full-year revenue guidance to about $67.6 billion — that's the second raise this year, $600 million total.

    JORDAN: What jumps out to me is the breadth of the growth. It's not just one drug carrying the load. SKYRIZI, RINVOQ, and the entire neuroscience portfolio all grew north of 20%. SKYRIZI alone did $5.5 billion in the quarter, up 24%. RINVOQ crossed $2.5 billion, up almost 24%.

    ALEX: And that's the story that matters most for AbbVie long-term — how well they've replaced the HUMIRA revenue. Speaking of which, HUMIRA sales were down 36% due to biosimilar competition, but that's expected and honestly just noise at this point given how much SKYRIZI and RINVOQ have scaled up.

    JORDAN: Right, HUMIRA is basically a rounding error now compared to where the immunology franchise is headed. Immunology overall did $8.8 billion, up nearly 15%.

    ALEX: Let's talk strategy, because the big headline this quarter was the announced acquisition of Apogee Therapeutics. This adds assets in dermatology, respiratory, and other inflammatory diseases — basically deepening that immunology pipeline for the 2030s and beyond.

    JORDAN: It's a dilutive deal in the near term — CFO Scott Reents said it's adding about 14 cents of dilution to full-year EPS guidance, which actually more than offset the underlying business over-performance in the updated guidance. But management framed it as setting up growth well past SKYRIZI and RINVOQ's patent cliffs.

    ALEX: Which, by the way, got some clarity on this call too. SKYRIZI's composition patent expires in 2033, but CEO Rob Michael pointed out regulatory data protection runs through 2031, and they don't expect biosimilar filings until the end of the decade. So that runway is longer than some investors might assume.

    JORDAN: The other big strategic thread was dermatology — RINVOQ picked up European approvals in vitiligo and alopecia areata, and management now sees combined peak sales for those two indications approaching $2 billion, which is well above what they'd previously guided.

    ALEX: There was a great exchange in the Q&A about that too — an analyst pushed on how crowded the vitiligo landscape is getting with other mechanisms coming in. Jeff Stewart's response was basically: these immunology markets keep proving to be way more expansive than people expect once a real systemic treatment shows up, and RINVOQ has the head start plus a decade of safety data behind it.

    JORDAN: I also want to flag the SKYRIZI subcutaneous induction story in Crohn's disease — that's got an FDA decision expected this fall. Jeff said they expect a "meaningful acceleration" in SKYRIZI's growth once that's approved, partly because it lets physicians avoid juggling two different reimbursement channels. Management expects that benefit to really show up in early 2027.

    ALEX: On the pipeline side, there's a lot cooking beyond immunology too. Parkinson's is shaping up as a real growth story — tavapadone has an FDA decision expected in Q3, and Vyalev is on track for blockbuster status this year. Management still sees the Parkinson's franchise collectively hitting more than $5 billion in peak sales.

    JORDAN: Oncology got some att

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  • Bristol-Myers Squibb Q2 2026 Earnings Analysis

    Bristol-Myers Squibb Q2 2026 Earnings Analysis
    2026/07/31
    More earnings analysis: https://betafinch.com
    Groups: PHARMA (https://betafinch.com/groups/PHARMA)
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    ALEX: Welcome to Beta Finch, your AI-powered earnings breakdown! Today we're digging into Bristol Myers Squibb's second quarter 2026 results, reported Thursday morning. Before we get into it, quick disclaimer: this podcast is AI-generated content for educational and entertainment purposes only. Nothing we discuss should be considered investment advice. Always do your own research and consult a qualified financial advisor before making any investment decisions.

    JORDAN: And BMY shares were up nearly 2.8% on the news, so investors clearly liked what they heard. Let's get into the numbers.

    ALEX: Total revenue for Q2 came in around $13 billion, up 5% year-over-year. The headline story here is what they call the "growth portfolio" — that's their newer drugs — now making up almost 60% of total revenue, growing 14%. Ten different products posted double-digit growth.

    JORDAN: That's the story management really wants you to hear — they're successfully transitioning away from legacy products losing patent protection, toward newer assets. And the standouts were impressive: Reblozyl up 29%, Breyanzi up 41%, Camzyos up 59%, and Qvantig — the newer version of their big cancer drug Opdivo — now annualizing over $1 billion.

    ALEX: Meanwhile, on the "legacy" side, Eliquis, their blood thinner, actually grew 21% on strong demand, which helped offset declines elsewhere from generic competition, especially as Revlimid keeps facing generics.

    JORDAN: Diluted EPS was $2.04 for the quarter, and gross margin held at 71.4%. And because of this strength, management raised full-year guidance for both revenue and adjusted EPS.

    ALEX: They also raised their Eliquis growth expectation for the year to 20-25%, and said the overall legacy portfolio decline will be less severe than previously thought — now 4-6% instead of worse.

    JORDAN: Balance sheet's solid too — $11.5 billion in cash, $3.4 billion in operating cash flow for the quarter, and they paid down $1.2 billion in debt. So they've got room to keep investing.

    ALEX: Now let's talk strategy, because there's a lot happening on the pipeline side. CEO Chris Boerner talked about the company potentially launching more than 10 new medicines by the end of the decade, plus over 30 lifecycle management opportunities.

    JORDAN: The near-term catalyst everyone's watching is iberdomide — that's their CELMoD, a new class of oral drug for multiple myeloma. It has an FDA decision date of August 17th, so basically two weeks after this call. If approved, it'd be the first commercialized CELMoD ever.

    ALEX: And there's a second one right behind it — mezigdomide — which just got its FDA application accepted with a target decision date of May 2027. Management's pretty bullish these two drugs, along with a third one called golcadomide, could eventually replace older myeloma standards like Revlimid and Pomalyst.

    JORDAN: But here's the more nuanced part of the call — two of their biggest pipeline bets just got delayed. Milvexian, a next-generation blood thinner they're developing with Johnson & Johnson... wait, actually it's with partners on the anticoagulant side, competing against their own Eliquis franchise — its atrial fibrillation trial readout got pushed from late 2026 to Q1 2027.

    ALEX: And separately, Cobenfy — their schizophrenia drug that they're also testing in Alzheimer's-related psychosis — those readouts are now expected to start in early 2027 instead of this year.

    JORDAN: Now, management was pretty insistent both delays are actually good news in disguise. For milvexian, it's an event-driven trial — meaning they need a certain number of stroke and bleeding events to occur before they can read the data. Fewer events happening means the drug might be working better than expected. Chief Medical Officer Cristian Massacesi even pointed out that a competitor's similar trial got stopped early for going the w

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  • Regeneron Q2 2026 Earnings Analysis

    Regeneron Q2 2026 Earnings Analysis
    2026/07/31
    More earnings analysis: https://betafinch.com
    Groups: PHARMA (https://betafinch.com/groups/PHARMA)
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    ALEX: Welcome to Beta Finch, your AI-powered earnings breakdown! Today we're digging into Regeneron's second quarter 2026 results, and Jordan, this was a big one.

    JORDAN: A really strong quarter across the board. But first, the standard note — this podcast is AI-generated content for educational and entertainment purposes only. Nothing we discuss should be considered investment advice. Always do your own research and consult a qualified financial advisor before making any investment decisions.

    ALEX: Right. So let's set the scene — before diving into numbers, the call opened with a tribute to longtime board member Art Ryan, who passed away this week. He'd been on Regeneron's board for over two decades, previously ran Prudential. A nice moment of the human side of these calls.

    JORDAN: Definitely worth noting. Now, onto the business — total revenue was up 17% year-over-year to $4.3 billion, and non-GAAP EPS grew 11% to $14.29. That's their second straight quarter of double-digit growth on both lines.

    ALEX: And the headline here is really the trio of record quarters — Dupixent, EYLEA HD, and Libtayo all hit all-time highs for quarterly sales.

    JORDAN: Let's start with Dupixent since it's the big one. Global net sales hit $6 billion, up 38% on a constant currency basis. U.S. sales alone grew 42% to $4.6 billion. That's a drug now serving over 1.5 million patients across nine approved indications.

    ALEX: Nine! That's dermatology, asthma, nasal polyps, COPD, eosinophilic esophagitis — it just keeps expanding. And here's something investors should watch: Regeneron fully repaid its $3.1 billion development balance owed to Sanofi. That balance had been suppressing collaboration revenue — about $930 million lower in 2025 and $530 million in the first half of this year.

    JORDAN: So starting in Q3, Regeneron gets to keep its full share of collaboration profits. That's a real step-up to the bottom line going forward, not tied to any new sales growth — just an accounting unlock.

    ALEX: Exactly. Now let's talk EYLEA HD — this one's on fire. U.S. net sales just under $600 million, up 52% year-over-year. And notably, this was the first quarter EYLEA HD sales actually exceeded the original EYLEA.

    JORDAN: That's the conversion story playing out. EYLEA HD now makes up about 60% of the franchise, up from 34% a year ago. Meanwhile legacy EYLEA sales fell 45% as patients and doctors shift over — plus there's now biosimilar competition entering that older product's market.

    ALEX: They're also awaiting FDA approval on an EYLEA HD prefilled syringe, which could drive even more adoption. Management sounded confident that could land by year-end.

    JORDAN: And rounding out the trio, Libtayo — their oncology drug — hit $489 million globally, up 29%. It's gaining real traction in non-small cell lung cancer, now capturing 20% of new prescriptions, double what it was just last year.

    ALEX: Let's talk pipeline for a second, because Regeneron's whole philosophy here is "don't bet on one horse." They've got roughly 50 active clinical programs.

    JORDAN: A few near-term catalysts stood out to me. There's cemdisiran, their siRNA therapy for myasthenia gravis, with an FDA decision expected in November — that could be the first siRNA approved for that disease. There's also garetosmab for a rare bone disease called FOP, with an FDA decision expected as soon as August.

    ALEX: And on the bigger picture front, they're moving into Phase III trials later this year for both their obesity program — a GLP-GIP combo called olatorepatide — and their anticoagulation program targeting Factor XI, which is a different approach than the traditional blood thinners on the market.

    JORDAN: One thing that came up repeatedly in Q&A was the Sanofi relationship. CEO Leonard Schleifer confirmed they're in "productive early discussions" with Sanofi about expanding the collaboratio

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    7 分
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