『Ayurveda's answer to Parkinson』のカバーアート

Ayurveda's answer to Parkinson

Ayurveda's answer to Parkinson

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 Overview: A Breakthrough in Ayurvedic TreatmentResearchers have identified Lasunadya Ghrita (LG), a traditional Ayurvedic formulation, as a promising treatment for neurodegenerative diseases. While conditions like Alzheimer’s and Parkinson’s were previously considered manageable but incurable, this discovery by the Bose Institute in Kolkata (under the Department of Science and Technology) offers a potential path toward reversing protein damage in the brain.Understanding Neurodegenerative DiseasesDefinition: These are conditions characterized by the progressive damage and eventual destruction of the nervous system, particularly the brain.Progression: Symptoms typically manifest later in life and worsen over time.Common Types: Includes Alzheimer’s disease, Parkinson’s disease (PD), Dementia, and Amyotrophic Lateral Sclerosis (ALS).The Role of Amyloid ProteinsThe primary driver of these diseases is the formation of toxic protein clusters.Protein Strains: Specific proteins like amyloid beta (Aβ) and tau (Alzheimer’s), α-synuclein (Parkinson’s), and TDP-43 (ALS) are the main culprits.Aggregation: These naturally disordered proteins group together into dense clusters called biomolecular condensates or amyloid plaques.Impact: These clusters disrupt cellular function and lead to the death of neurons.Lasunadya Ghrita (LG) as a Potential CureThe research team at the Bose Institute repurposed this traditional medicine, originally used for depression-related mental illnesses, to fight neurodegeneration.Mechanism of Action: An aqueous extract of the medicine (LGWE) was found to disrupt the "fibrillation process"—the stage where harmful proteins elongate and clump together.Early Intervention: It stops the formation of oligomers (early-stage toxic clusters) in the fibrillation pathway.Superior Efficacy: LGWE proved more effective than chemically synthesized peptides at breaking down existing amyloid aggregates into harmless, degradable molecules.Safety: The components of LG are non-toxic and have been modified for maximum effectiveness against amyloid beta 40/42.Key Ingredients and Their Neuroprotective BenefitsLasunadya Ghrita is a complex blend of natural ingredients, each contributing specific therapeutic properties:IngredientPrimary BenefitFunctional RoleGarlicAntioxidant PowerContains allicin; reduces oxidative stress and safeguards against cognitive deterioration.Dried GingerAnti-inflammatorySuppresses inflammatory processes in the brain; helps prevent multiple sclerosis and age-related decline.Black PepperPlaque ReductionContains piperine, which enhances memory and reduces the formation of dense amyloid plaques.Raw HoneyNeuroprotectionMitigates oxidative stress, boosts mood, and lowers the risk of metabolic syndrome linked to Alzheimer's.Other ComponentsSynergistic SupportIncludes aged ghee and asafoetida, traditionally used to enhance the bioavailability of the herbs.
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