In this episode of Updates in Anesthesiology, Dr. Hadzic discusses the main findings from a 2025 BJA review by Tinsley et al. The study reported how to manage non-insulin diabetes medicines in the perioperative period safely. From metformin’s misunderstood safety profile to the hidden risks of SGLT-2 inhibitors and GLP-1 agonists, you’ll learn which drugs to hold, which to continue, and how to prevent complications like euglycaemic DKA and aspiration.

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Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

A 2025 Anesthesiology meta-analysis shows that the best pain control after total hip arthroplasty comes from combining regional anesthesia with local infiltration analgesia (LIA). While LIA alone is effective, adding a quadratus lumborum or pericapsular nerve group (PENG) block significantly improves pain relief, reduces opioid use, and preserves mobility. The takeaway: stop choosing between techniques — regional + local is the new gold standard for hip surgery analgesia.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠

Facebook- ⁠⁠facebook.com/nysora⁠⁠

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--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic unpacks a landmark 2025 study, which challenges the long-held belief that intraoperative hypotension (MAP < 65 mm Hg) contributes to postoperative delirium in older adults. With nearly 40,000 patients analyzed and no association found, it’s time to rethink reflexively chasing MAP thresholds. Tune in to hear why blood pressure might not be the villain we thought, and what really matters for preventing POD.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠

Facebook- ⁠⁠facebook.com/nysora⁠⁠

Twitter- ⁠⁠x.com/nysora⁠⁠

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.