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In this episode of Health in Hyperdrive, Dominic James is joined by Hakim Yadi PhD OBE, a biotech entrepreneur and industry leader, to explore one of the biggest shifts in modern healthcare: precision medicine. They look at how data, genomics, AI and smarter drug development are helping us move beyond standardised treatment.

Precision medicine has the potential to change how we treat people, not just conditions. By combining real-world data with pharmacology, it helps move care away from generic averages and towards what actually works for each individual. That means fewer side effects, better results, and a stronger chance patients stay on treatment. It is not just good medicine, it is smarter, fairer, and more sustainable for health systems like the NHS. In fact, adverse drug reactions cost the NHS an estimated £2 billion a year, and precision approaches could help bring that number down significantly.

Together, Dominic and Hakim explore how this approach can improve outcomes, reduce health inequalities, and make treatment more tolerable. They also dive into GLP-1 therapies, the push for better women’s health, and the business model challenges that still slow innovation. Along the way, they ask what it would take to make personalised care the standard, not the exception.

Key Topics Covered

• Why most drug dosages are still based on outdated trial data
• The rise of GLP-1 therapies and what they mean for patient experience
• The dangers of self-dosing advice on Reddit, TikTok and Instagram
• The business model challenge behind scaling innovation
• Why personalised care benefits patients and health systems
• What it means to “nibble” a medicine in 2025
• How health data saves lives and why we should all donate data
• The North–South health divide in England and its link to 1 million premature deaths
• In 2035, our Children today will view medicine today as draconian

About Hakim

Hakim Yadi PhD OBE is a biotech entrepreneur and Partner at Baringa, focused on global health innovation.

He co-founded Closed Loop Medicine, delivering personalised care through drug and digital integration.

With a PhD in immunology and an OBE awarded for services to healthcare technology and the economy, Hakim bridges clinical innovation with system transformation.

Links

• Hakim’s LinkedIn - https://www.linkedin.com/in/hakimyadi/
• Baringa website - https://www.baringa.com/en/people/experts/hakim-yadi/
• Closed Loop Medicine website - https://closedloopmedicine.com/
• Data saves lives website - https://datasaveslives.eu/
• Dominic’s LinkedIn - https://www.linkedin.com/in/dominicjames
• Health in Hyperdrive website - https://www.healthinhyperdrive.com
• Socials TikTok / X / Insta / YouTube - @DomJamesHiH
• Produced by Explosive Brands - https://www.explosivebrands.com/