Welcome back to The Holistic GLP-1 Podcast—the number-one show on Spotify and Apple Podcasts exploring a healthy and mindful approach to GLP-1 technologies, before, during and after the use of the actual medication.

Today, we're joined by Dr. Andrew Shapiro, a leading breast-cancer surgeon and Medical Director of Advanced Surgical Physicians in Palm Beach County, Florida. Dr. Shapiro shares how GLP-1 medications like semaglutide and tirzepatide are transforming life after breast cancer—helping women regain metabolic balance, body confidence and a renewed sense of health.

Together, we discuss the intersection of hormones, inflammation and weight management; why estrogen and insulin play pivotal roles in midlife health; and how a personalized, mindful approach to GLP-1 therapy can protect muscle, improve energy and promote lasting wellness.

If you've ever wondered how GLP-1s fit into holistic cancer recovery and women's hormonal health — this episode will change the way you think about healing from the inside out.

[ 00:00 ] Introduction

[ 01:30 ] Dr. Shapiro's personal story; his wife's autoimmune illness and first-hand success with GLP-1s

[ 03:35 ] Integrating GLP-1s into breast-cancer follow-up care; addressing post-treatment weight gain and hormonal medications

[ 06:20 ] Safe timing for GLP-1 use after cancer treatment; improving quality of life for survivors

[ 09:00 ] Sugar, metabolism & cancer growth; nutrition principles for cancer prevention and recovery

[ 12:30 ] Mindset, lifestyle & community support in holistic healing

[ 15:00 ] GLP-1 benefits beyond diabetes

[ 18:20 ] Nutritional guidance: protein first, hydration, mindful eating

[ 21:20 ] Individualized dosing & compounded tirzepatide; role of B12 and glycine for energy and muscle support

[ 25:00 ] Preserving lean muscle mass and simple at-home strength training

[ 28:00 ] Estrogen, obesity, and breast-cancer risk

[ 31:00 ] Insulin regulation, menopause, and hormonal balance

[ 34:30 ] Evolving approaches to menopause care and hormone therapy

[ 37:00 ] Tapering off GLP-1 medications & long-term maintenance

[ 40:00 ] Future applications of GLP-1s in autoimmune and metabolic medicine

[ 43:00 ] Integration of bariatric surgery and medical weight management

[ 46:00 ] Closing message: empowering women to thrive after breast cancer

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Learn more about Dr. Andrew Shapiro & His Practice:

Website: https://www.toplinemd.com/advanced-surgical-physicians/

Instagram: https://www.instagram.com/advancedsurgicalphysicians/