Mayo Clinic Guide to Gut Health
Restore Your Microbiome, Enhance Digestion, and Improve Your Health from the Inside Out
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Mayo Clinic Guide to Gut Health
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Lyle Blaker
A comprehensive guide to understanding your gut, its influence on your health, and what you can do to protect it.
Digestion may be its primary job, but your gut is pulling double duty behind the scenes. Sometimes referred to as the body’s “second brain,” your gut plays an important role in everything from immunity and brain function to metabolism and skin health.
Within your gut resides a bustling community of trillions of microorganisms working 24/7 to fight off harmful invaders, create essential nutrients, and keep your body running like a well-oiled machine. When this delicate ecosystem, known as the gut microbiome, is thrown off balance, it can trigger a range of health issues.
Mayo Clinic Guide to Gut Health is an expert-driven resource from Mayo Clinic gastroenterologists that explores everything you need to know to take control of digestive issues.
©2026 Mayo Foundation for Medical Education and Research (MFMER)