『Drug Monitoring and Clinical Chemistry』のカバーアート

Drug Monitoring and Clinical Chemistry

Drug Monitoring and Clinical Chemistry

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概要

 A technical handbook focused on the intersection of therapeutic drug monitoring (TDM) and clinical chemistry. It highlights the evolution of analytical methods, such as capillary electrophoresis and immunoassays, which allow for the precise measurement of drug levels in biological fluids. The sources emphasize the transition from generic dosing to individualized drug therapy, utilizing pharmacokinetic and pharmacodynamic models to improve patient outcomes. Additionally, the material explores the emerging role of pharmacogenomics, describing various genotyping technologies used to identify genetic variations that affect drug metabolism. By integrating laboratory validation standards with clinical case studies, the text illustrates how model-based monitoring can minimize toxicity and enhance the cost-effectiveness of treatments. Overall, the volume serves as a comprehensive guide for clinicians and researchers to optimize pharmacotherapy through advanced chemical analysis.

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